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ADME DB

 

ADME DB is a database containing information on metabolic processes facilitated by Human Cytochrome P450 enzymes. The information is organized by category (therapeutic area), drug name, enzyme, reaction, and type. ADME DB has been developed by Prof. Slobodan Rendić of the University of Zagreb. The database is intended for scientists involved in the drug discovery research.

The service is available to through the Internet on a subscription basis.

Contents

Human P450 Metabolism Database

  • Provides information on 50 CYP enzymes and a number of variants, which participate in the metabolism of xenobiotics and endobiotics in humans
  • Contains over 13 000 entries
  • Contains data on more than 6 500 substances, including a number of natural products
  • Contains data collected from more 3 000 citations

Kinetic Metabolism Database

  • Database contains over 11 000 entries extracted from Human Cytochrome P450 metabolism database references, providing numerical data on major kinetic parameters relevant for use in drug development/application studies.

Human Transporter Database

  • Provides information on more than 256 Transporters involved in drugs transport, as well as on the associated physiological compounds, nutrients, and other chemicals and metabolites.
  • ABC Transporter
  • Organic Ion Transporter
  • Peptide Transporter
  • Nucleotide Transporter etc.

 

 

 
     
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